Chun Wang MD, PhD, Jianqiu Xiao PhD, Gabriel Mbalaviele PhD, and colleagues published a paper in Science Immunology in which they discovered an unexpected function of the NLRP3 inflammasome in inflammation in the absence of gasdermin D.
Citation: NLRP3 inflammasome activation triggers gasdermin D-independent inflammation. Wang C, Yang T, Xiao J, Xu C, Alippe Y, Sun K, Kanneganti TD, Monahan JB, Abu-Amer Y, Lieberman J, Mbalaviele G. Sci Immunol. 2021 Oct 22;6(64):eabj3859. doi: 10.1126/sciimmunol.abj3859. Epub 2021 Oct 22. PMID: 34678046.