From left to right: Mahshid Mohseni, MD, Director of the Clinical Research Unit; Mirnesa Brazeal, Bone Health medical assistant posing as a research participant; and Shannon Stum, Clinical Research Coordinator; standing next to the HR-pQCT.

The Clinical Research Unit (CRU) of the Division of Bone and Mineral Diseases supports investigators with projects requiring the assessment of clinically relevant bone outcomes and offers assistance with research subject recruitment and study management.

Established by our founder, Louis V. Avioli, MD, the CRU has been in operation for over twenty years. Historically, it has participated in clinical trials evaluating the efficacy of most of the currently available osteoporosis therapies.

Available to investigators are state-of-the-art bone imaging technologies, including dual-energy X-ray absorptiometry (DXA) units for assessment of bone mineral density and body composition, and a high-resolution peripheral quantitative computed tomography (HR-pQCT) scanner for assessment of bone microstructure and strength.

The CRU is currently directed by Mahshid Mohseni, MD, and its services and resources are available to investigators within or outside the division, on a fee-for-service basis.


  • HR-pQCT located at Center for Advanced Medicine – South County
    5201 Midamerica Plaza
    St. Louis, MO 63129
  • Center for Advanced Medicine, 11th floor, next to the Center for Clinical Studies
    4921 Parkview Place
    St. Louis, MO 63110
  • Barnes-Jewish West County Hospital, Medical Office Building 2, Suite 200
    10 Barnes West Drive
    Creve Coeur, MO 63141


For more information about current clinical studies, new research proposals, or access to skeletal imaging for clinical research, please contact:

Bridgett Toennies, RT, (R) (CBDT)
Clinical Research Coordinator