Christopher J. Hernandez, PhD Professor Sibley School of Mechanical and Aerospace Engineering Cornell University Ithaca, NY “The Microbiome and Orthopaedic Disorders”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom Meeting ID.

Samantha Chin Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk. (.pdf) Wang L, You X, Lotinun S, Zhang L, Wu N, Zou W. Nat Commun. 2020 Jan 15;11(1):282.   Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password

Suneel S. Apte, MBBS, DPhil Staff Department of Biomedical Engineering Cleveland Clinic Lerner Research Institute Cleveland, OH “Degradomics in the service of osteoarthritis and musculoskeletal developmental defects”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom Meeting ID.  

Anastasiia Onyshchenko Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization. (.pdf) Baccin C, Al-Sabah J, Velten L, Helbling PM, Grünschläger F, Hernández-Malmierca P, Nombela-Arrieta C, Steinmetz LM, Trumpp A, Haas S. Nat Cell Biol. 2020 Jan;22(1):38-48.   Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID […]

Katie Hixon, PhD Postdoc Research Scholar Department of Orthopaedic Surgery Silva Lab Washington University “Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom Meeting ID.

Jenn Davis PD-1 blockade inhibits osteoclast formation and murine bone cancer pain. (.pdf) Wang K, Gu Y, Liao Y, Bang S, Donnelly CR, Chen O, Tao X, Mirando AJ, Hilton MJ, Ji RR. J Clin Invest. 2020 Jul 1;130(7):3603-3620.   Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password

Simon Tang, PhD Associate Professor Department of Orthopaedic Surgery Washington University “Development of Imaging Biomarkers for Low Back Pain”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom Meeting ID.

Anne Camus, PhD Senior Academic Skeletal Physiopathology and Joint Regenerative Medicine RMeS – Regenerative Medicine and Skeleton INSERM, University of Nantes Nantes, France “Intervertebral disc: A journey from embryonic development to cell-based regenerative strategy”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom Meeting ID.

Reggie Aurora Warmth Prevents Bone Loss Through the Gut Microbiota. (.pdf) Chevalier C, Kieser S, Çolakoğlu M, Hadadi N, Brun J, Rigo D, Suárez-Zamorano N, Spiljar M, Fabbiano S, Busse B, Ivanišević J, Macpherson A, Bonnet N, Trajkovski M. Cell Metab. 2020 Oct 6;32(4):575-590.e7.   Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting […]

Christa Maes, PhD Associate Professor Department of Development and Regeneration Skeletal Biology and Engineering Research Center KU Leuven Leuven, Belgium “Skeletal Stem and Progenitor Cells (SSPCs) in Bone Growth, Homeostasis and Repair”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Erica Scheller, DDS, PhD Assistant Professor Department of Medicine, Division of Bone and Mineral Diseases Washington University “Neural Contributions to Skeletal Health and Pathophysiology”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Terence Capellini, PhD Richard B. Wolf Associate Professor Department of Human Evolutionary Biology Harvard University Cambridge, MA “The regulation of skeletal development and disease”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.  

Toshifumi Sugatani Regulation of body length and bone mass by Gpr126/Adgrg6 (.pdf) Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J, Liu M, Luo J. Sci Adv. 2020 Mar 20;6(12):eaaz0368.     Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and […]

Lori Setton, PhD Lucy & Stanley Lopata Distinguished Professor and Chair Department of Biomedical Engineering Washington University “Musculoskeletal cross-talk with the nervous system – Works in progress”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.  

Nicholas Semenkovich JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function. (.pdf) Adam S, Simon N, Steffen U, Andes FT, Scholtysek C, Müller DIH, Weidner D, Andreev D, Kleyer A, Culemann S, Hahn M, Schett G, Krönke G, Frey S, Hueber AJ. Sci Transl Med. 2020 Feb […]

Patricia Dickson, MD Centennial Professor of Pediatrics Department of Pediatrics Genetics & Genomics Medicine Washington University “Therapeutic approaches to bone and joint disease in the mucopolysaccharidoses”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Shawn Lee A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia. (.pdf) Baryawno N, Przybylski D, Kowalczyk MS, Kfoury Y, Severe N, Gustafsson K, Kokkaliaris KD, Mercier F, Tabaka M, Hofree M, Dionne D, Papazian A, Lee D, Ashenberg O, Subramanian A, Vaishnav ED, Rozenblatt-Rosen O, Regev A, Scadden DT. Cell. 2019 […]

Suresh Adapala Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. (.pdf) Alivernini S, MacDonald L, Elmesmari A, Finlay S, Tolusso B, Gigante MR, Petricca L, Di Mario C, Bui L, Perniola S, Attar M, Gessi M, Fedele AL, Chilaka S, Somma D, Sansom SN, Filer A, McSharry C, Millar NL, Kirschner […]

Short Talks by Musculoskeletal Research Center Award Recipients and Trainees: Gabriel Haller, PhD (MRC Pilot & Feasibility Award) Assistant Professor of Neurological Surgery “Zebrafish models of genes associated with Chiari I malformation” Austin Hensley PhD Student, McAlinden Lab, Orthopaedic Surgery “Modulation of microRNAs to engineer a layered osteochondral tissue construct” Feini  (Sylvia) Qu, VMD, PhD […]

Gabriel Mbalaviele Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis. (.pdf) O’Neil LJ, Barrera-Vargas A, Sandoval-Heglund D, Merayo-Chalico J, Aguirre-Aguilar E, Aponte AM, Ruiz-Perdomo Y, Gucek M, El-Gabalawy H, Fox DA, Katz JD, Kaplan MJ, Carmona-Rivera C. Sci Adv. 2020 Oct 28;6(44):eabd2688.   Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and […]

Anna Spagnoli, MD John W. and Helen H. Watzek Professor Orthopaedic Surgery and Pediatrics Director, Section of Molecular Medicine Rush University Medical Center Chicago, IL “Progenitors in Bone and Cartilage Development, Homeostasis and Repair”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Deborah Veis, MD, PhD Professor Department of Medicine Division of Bone and Mineral Diseases Washington University “‘Staphing’ the bone: bug-bone interactions in osteomyelitis”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Deb Veis Human and mouse bones physiologically integrate in a humanized mouse model while maintaining species-specific ultrastructure. (.pdf) Moreno-Jiménez I, Cipitria A, Sánchez-Herrero A, van Tol AF, Roschger A, Lahr CA, McGovern JA, Hutmacher DW, Fratzl P. Sci Adv. 2020 Oct 28;6(44):eabb9265.     Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID […]

Matthew Goodwin, MD, PhD, FACSM Assistant Professor Departments of Orthopaedic Surgery and Neurosurgery Washington University “Lactate in the spine: from tumors to discs”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Tim Peterson Locally renewing resident synovial macrophages provide a protective barrier for the joint. (.pdf) Culemann S, Grüneboom A, Nicolás-Ávila JÁ, Weidner D, Lämmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, […]

Nidhi Rohatgi Environmental arginine controls multinuclear giant cell metabolism and formation. (.pdf) Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O’Shea JJ, Weichhart T, Meissner F, Smolen […]

Noriaki Ono, DDS, PhD Associate Professor Department of Orthodontics & Pediatric Dentistry University of Michigan School of Dentistry Ann Arbor, MI “Stem cells in bone development, diseases and regeneration”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.

Gaurav Swarnkar CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts. (.pdf) Slowikowski K, Nguyen HN, Noss EH, Simmons DP, Mizoguchi F, Watts GFM, Gurish MF, Brenner MB, Raychaudhuri S. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5532-5541.   Schedule of presenters Email Christina Grantham (granthamc@wustl.edu) […]

Holly Ingraham, PhD Herzstein Endowed Professor and Associate Vice Chairman Department of Cellular and Molecular Pharmacology UCSF San Francisco, CA “The Central Female Power Grid Controlling Energy and Bone Metabolism”   Please email Christina Grantham (granthamc@wustl.edu) for Zoom meeting ID and password.