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Nicola Napoli, MD, PhD

Adjunct Research Assistant Professor of Medicine


Junior Career Award, X Annual Meeting of the Società Italiana per l’Osteoporosi e Malattie del Metabolismo Minerale, Brescia, Italy, 2010
August and Marie Krogh Award, 2009
Best Clinical Paper, IX Annual Meeting of the Società Italiana per l’Osteoporosi e Malattie del Metabolismo Minerale, Torino, Italy, 2009
Young Investigator Lecture, VIII Annual Meeting of the Società Italiana per l’Osteoporosi e Malattie del Metabolismo Minerale, Perugia, Italy, 2008
Young Research Investigator Award, American Society for Bone and Mineral Research, Montreal, Canada, 2008
Young Investigator Award, 3rd Androgen Excess Society Meeting, San Diego, 2005
Young Investigator award, 105° Congresso Nazionale della Società Italiana di Medicina Interna, 2004

Research Interests

Dr. Napoli’s research interests focus on pharmacogenetics of osteoporosis, with emphasis on estrogen metabolic pathways, on the effects of bisphosphonates and other pharmacologic agents in osteoporosis, and on the effects of diabetes on bone health. He is also engaged in health advocacy activities in developing countries, in collaboration with other Italian Universities as well as Harvard Medical School.


Napoli N, Varadharajan A, Rini GB, Del Fiacco R, Yarramaneni J, Mumm S, Villareal DT, Armamento-Villareal R. Effects of polymorphisms of the sex hormone-binding globulin (SHBG) gene on free estradiol and bone mineral density. Bone. 2009 Dec;45(6):1169-74.
Napoli N, Novack D, Armamento-Villareal R. Bisphosphonate-associated femoral fracture: implications for management in patients with malignancies. Osteoporos Int. 2010 Apr;21(4):705-8.
Napoli N, Pedone C, Pozzilli P, Lauretani F, Ferrucci L, Incalzi RA. Adiponectin and bone mass density: The InCHIANTI study. Bone. 2010 Dec;47(6):1001-5.
Bizzarri C, Pitocco D, Napoli N, Di Stasio E, Maggi D, Manfrini S, Suraci C, Cavallo MG, Cappa M, Ghirlanda G, Pozzilli P; IMDIAB Group. No protective effect of calcitriol on beta-cell function in recent-onset type 1 diabetes: the IMDIAB XIII trial. Diabetes Care. 2010 Sep;33(9):1962-3.
Napoli N, Vattikuti S, Ma C, Rastelli A, Rayani A, Donepudi R, Asadfard M, Yarramaneni J, Ellis M, Armamento-Villareal R. High prevalence of low vitamin D and musculoskeletal complaints in women with breast cancer. Breast J. 2010 Nov-Dec;16(6):609-16.
Rizzoli R, Akesson K, Bouxsein M, Kanis JA, Napoli N, Papapoulos S, Reginster JY, Cooper C. Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporos Int. 2010 Nov 18. [Epub ahead of print]

Editorial Responsibilities

Reviewer: Bone, Osteoporosis International, Calcified Tissue International, Diabetes- Obesity and Metabolism, Maturitas.

Professional Societies and Organizations

  • American Society for Bone and Mineral Research
  • Endocrine Society
  • European Calcified Tissue Society
  • International Osteoporosis Foundation – Scientific Advisory Committee Member

Current Prime Affiliation:

Campus: Biomedico Roma, Rome, Italy
Office: +39-062-254-19151
Fax: +39-062-254-1456